Integrative Protein Biology Program

The Institute's ongoing effort to understand how body structures, disease and other processes lead to body tissue loss or dysfunction will lead to the successful treatment of Alzheimer's disease, muscular dystrophy, diabetes and stroke. By learning how muscles grow and deteriorate and what role specific proteins play in these processes, our team will discover how to promote muscle regeneration.

Infectious diseases can also be addressed in Protein Biology. One of the initiatives underway uses biophysical tools to elucidate the molecular mechanisms by which bacterial toxins cause deadly diseases such as toxic shock syndrome and to develop life-saving therapies. Another program uses a chemical biology approach for the development of novel antibiotics against the TB bacillus which can be used to treat multidrug-resistant tuberculosis without eliciting the development of further drug resistance.