Disease Relevance

Basic research programs of BBRI scientists are leading to an understanding of the causes of a diversity of human diseases and to the development of new therapeutics.

Aging – Wohlrab

Alzheimer’s Disease – Raso

Angiogenesis – Emerson

Asthma – Graceffa, Morgan, Tao, Wang

Bacterial Pathogenesis – Paulus, Sarkar, Sundberg

Bacterial Virulence – Sarkar

Brain Cancer – Emerson

Breast Cancer – Rameh

Cardiovascular Disease – Dominguez, Gergely, Graceffa, Erhardt, Fessenden, Ikemoto

Cell Death – Dominov, Erhardt, Miller

Central Core Disease – Fessenden, Ikemoto

Defense against Infection – Dominguez, Smith

Diabetes – Rameh, Wohlrab

Endometriosis – Gonzalez, Leavis

Epithelial Cancers – Hansen

Fertility – Gonzalez

Glycogen Storage Disease – Wohlrab

Hearing Loss – Coluccio, Lehrer

Heart Failure – Tao

Huntington’s Disease – Stafford

Indigestion – Wang

Ischemic Heart Disease – Erhardt

Malignant Hyperthermia – Fessenden, Ikemoto

Mental Retardation – Lu

Miscarriages – Morgan, Wang

Muscle Cancer – Emerson

Muscular Dystrophies – Dominov, Miller

Neural and Skeletomuscular Birth Defects – Emerson

Neural Degenerative Diseases – Dominov, Miller, Raso

Obesity – Rameh, Raso, Wohlrab

Pancreatic Cancer-Emerson

Parkinson’s Disease – Miller

Preterm Labor – Morgan

Skeletal Muscle Damage and Repair – Dominov, Miller, Raso

Skin Cancer – Emerson

Toxins and Superantigens – Sundberg

Tuberculosis – Paulus

Tumor Growth – Emerson, Erhardt, Hansen, Leavis, Rameh

Tumor Metastasis – Coluccio, Dominguez, Goldberg, Hansen, Smith

Vascular Disease – Emerson, Kitazawa, Morgan, Wang

Wound Healing – Coluccio, Dominguez, Hansen, Smith