Cancer Biology Program

Boston Biomedical Research Institute scientists are studying one of the most deadly types of cancer, derived from stem cells. This involves a very broad approach that takes advantage of expertise in cell-signaling to address the faulty signaling that leads to uncontrolled growth, in proteomics which is helping to dissect the aberrant signaling pathways, in cellular motility which plays a key role in cancer metastasis, in extra cellular matrix which can investigate how to keep cells within their “matrix environment”, and in stem cell biology which can shed light on the mechanisms by which stem cells can turn into cancer cells.

By discovering how cells normally respond to protein signals and how they migrate, the Institute’s Cancer Biology Program can better identify the components of faulty signaling pathways that contribute to cancer onset and progression. Our discovery efforts are critical in the development of new effective oncology therapeutics.