Monomeric actin in the ATP and ADP states

Otterbein et al., 2001. Science 293:708-711.

Graceffa & Dominguez, 2003. J. Biol. Chem. 278:34172-34180.

PDB: 1J6Z, 1NWK

Animation - Actin from ATP to ADP

Vitamin-D binding protein (DBP) by itself and complexed with actin

Otterbein et al., 2002. PNAS 9:8003-8008.

Movie - actin binding to DBP

Ca²⁺-free state

PDB: 1K8U, 1K9P

Myosin light chain Mlc1p bound to IQ motifs from the myosin V Myo2p heavy chain

Terrak et al., 2003. EMBO J. 22:362-371.

Terrak et al., 2002. Acta Crystallogr. D58:1882-1885.

Movie - Model of the myosin V lever arm

Smooth muscle myosin

Dominguez et al. 1998. Cell 94:559-571.

PDB: 1BR1 , 1BR2 , 1BR4

Animation - The acto-myosin power stroke

DBP complexed with actin,

PDB: 1KXP

Extended conformation : Mlc1p-IQ4

PDB: 1M46

Compact conformation : Mlc1p-IQ3, Mlc1p-IQ2, and Mlc1p-IQ23

PDB: 1M45 , 1N2D

Uncomplexed DBP

PDB: 1KW2

Complex Between Protein Ser/Thr Phosphatase-1 and The Myosin Phosphatase Targeting Subunit 1 (MYPT1)

Terrak et al., 2004. Nature 429:780-784.

PDB: 1S70

Animation of the structure