Boston Biomedical Research Institute (BBRI) was founded in 1968 as an independent, nonprofit scientific research institute dedicated to basic biomedical research to promote the understanding, prevention and treatment of a wide range of illnesses, including cancer, heart failure, stroke, diabetes and Alzheimer’s Disease.
BBRI has over 100 biomedical researchers, including 27 faculty members, tackling complex questions about how the human body works at the cellular and molecular level. The Institute also provides training to post-doctoral fellows and to graduate and undergraduate students as part of its educational outreach.
BBRI has developed strong programs in related areas of cell motility, cell communication, cell growth, and protein structure.
BBRI’s basic research in muscle cell biology holds potential benefits for individuals with muscle-related illnesses such as cardiovascular disease, which affects over 60 million Americans each year – one quarter of our population.
BBRI has a growing group of cancer biologists with expertise in signal transduction and cell growth whose research is greatly enhanced by the equipment in the Cell Biology Core Facility, which is primarily funded through philanthropic support.
Examples of promising research programs currently underway at BBRI include a potential breakthrough in treating and preventing Alzheimer’s disease and an innovative method of attacking tuberculosis.
Modern medical advances, designed from the basic research findings of BBRI’s scientists include:
- One of the standard tests, the Troponin Assay, that is used by physicians to determine whether a person is having a heart attack; and the use of calcium blockers in the treatment of cardiac arrhythmias.
- Although not yet tested clinically, Troponin I has been identified as one of the most potent angiogenesis inhibitors known based on tests performed on an animal model system.
- The use of hyaluronan in cataract operations and in the treatment of osteoarthritis.
A Board of Trustees and Corporators, along with a Board of Overseers and a Scientific Advisory Committee, provide oversight and leadership to the Institute.